Cognitive impairment develops gradually in HD patients, progressing later into a severe cognitive dysfunction.
Huntington’s Disease (HD) is an autosomal neurodegenerative disease characterized by motor, cognitive, and psychiatric symptoms. Montreal Cognitive Assessment (MoCA) performance in Huntington’s disease patients correlates with cortical and caudate atrophy. Cite this article Ramirez-Garcia G, Galvez V, Diaz R, Campos-Romo A, Fernandez-Ruiz J. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. 3 Facultad de Medicina, Unidad Periférica de Neurociencias, Universidad Nacional Autónoma de México/Instituto Nacional de Neurologia y Neurocirugia, Ciudad de Mexico, Mexico DOI 10.7717/peerj.12917 Published Accepted Received Academic Editor Kevin Black Subject Areas Neuroscience, Neurology Keywords MoCA test, Huntington’s disease, Cortical thickness, Brain atrophy, Caudate volume Copyright © 2022 Ramirez-Garcia et al.
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